Although no real battles of the Revolutionary War were fought in Maine, Maine began rebelling against the assortment of British taxes early. Like in 1765 there were regular attacks on customs agents and once in Falmouth (now Portland) a group of men stole a large quantity of tax stamps.

In 1774 a mob of men burned a shipment of tea in York, an act much like the 1773 Boston Tea Party.

Maine men were also very involved with the Battle for Independence. On April 19, 1775 the first shots were fired at Lexington. By nightfall the word got spread through the York village. When they heard it, they immediately went to Boston on horseback to help fight. Some men were sent back to Maine so they could protect the town from raiding parties. In 1775, the British Captain Henry Mowatt told his warships to destroy and burn down Falmouth so as to punish Maine for its rebellion. There was also, off the Maine coast, a naval battle that occurred in June 1775 which captured a British cutter. Later that year a lot of Maine men got together with Colonel Benedict Arnold while they marched through the north woods to capture Quebec. Maine fought bravely in the American Revolution until 1781, when the British surrendered at Yorktown.